Civil servants from several ministries will take part in a month of sustained industrial action starting in mid-December.
PCS union members who work for the Home Office, Border Force, Department of Transport and Defra are seeking better pay and conditions.
Ports, borders and all areas of transport, including driving licenses, will be affected, as some workers will operate for the whole month while others will be absent for shorter periods.
PCS general secretary Mark Serwotka said the exact details of the action will be announced sooner to give the government as little notice as possible.
He said ministers should deal with the causes of the dispute rather than making contingency plans.
He added: “PCS members are angry.
“They have helped run this country during the pandemic and in return have been treated appallingly by this government.
He said: “With inflation now at 11.1%, it is inconceivable that they would have to face another pay cut in real terms.
“With tens of thousands of members on starvation wages, it’s no longer a matter of belt-tightening, it’s a choice between heating and eating – and that’s just not acceptable for the own workforce work of government.”
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The union wants a 10% pay rise, pension reform, job security and assurances that dismissal conditions will not be reduced.
Mr Serwotka repeated a suggestion he had made last month that coordinated action could be taken in the new year by joining other unions, such as those representing railway workers, university professors , firefighters, NHS staff and Royal Mail workers.
He called on Cabinet Office officials to “come back to the table ready to meet our demands”,
. officials go put strike affecting ports borders transport News UK